Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 15/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24068330 | 1.00 | SIRT2 (0.46) | SIRT2SIRT1SIRT3HTTFURIN | |
| SCHEMBL18823292 | 0.94 | SIRT2 (0.41) | SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL18823291 | 0.94 | SIRT2 (0.41) | SIRT2SIRT1SIRT3FURIN | |
| SCHEMBL25830938 | 0.93 | SIRT2 (0.42) | SIRT2SIRT1SIRT3 | |
| SCHEMBL23106392 | 0.93 | SIRT2 (0.42) | SIRT2SIRT1SIRT3 | |
| SCHEMBL18911016 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3HTTFURIN | |
| SCHEMBL20841069 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3HTTFURIN | |
| SCHEMBL22138818 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3HTTFURIN | |
| SCHEMBL20798913 | 0.92 | SIRT2 (0.42) | SIRT2SIRT1SIRT3HTTFURIN | |
| SCHEMBL23789221 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3HTTFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369853-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369853-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | PSMB1, MDM2, XIAP | SIRT2 2639/4885SIRT1 1897/4885SIRT3 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.