Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153090 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LMNACHRNA7SMN1; SMN2MEN1 | |
| SCHEMBL13532882 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LMNACHRNA7SMN1; SMN2MEN1 | |
| SCHEMBL13559795 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LMNACHRNA7SMN1; SMN2MEN1 | |
| SCHEMBL13559778 | 0.94 | CHRNA7 (0.38) | ALDH1A1LMNACHRNA7MEN1KMT2A | |
| SCHEMBL29138764 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21120632 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29335274 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28133521 | 0.81 | DPP4 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL13414049 | 0.81 | DPP4 (0.37) | ALDH1A1MEN1KMT2A | |
| Water SCHEMBL28133520 | 0.79 | CHRM2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |