Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21739460 | 0.80 | SPR (0.37) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL21739328 | 0.80 | SPR (0.37) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL18711619 | 0.79 | SPR (0.40) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL10305073 | 0.75 | SPR (0.38) | SPRKDM5AKMT2ANPC1RAB9A | |
| SCHEMBL23392344 | 0.73 | AKR1C3 (0.39) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL23392434 | 0.73 | AKR1C3 (0.39) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL23392436 | 0.73 | AKR1C3 (0.39) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL16516001 | 0.72 | SPR (0.38) | SPRSCN9AKDM5AKMT2ANPC1 | |
| SCHEMBL21739380 | 0.72 | KDM5A (0.39) | SPRKDM5AKMT2ANPC1RAB9A | |
| SCHEMBL16515572 | 0.72 | POLB (0.46) | SPRSCN9AKDM5AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |