Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923136 | 1.00 | CHRM2 (0.42) | CHRM2CHRM1CHRM3PIK3CDHSD17B10 | |
| SCHEMBL25698997 | 1.00 | CHRM2 (0.42) | CHRM2CHRM1CHRM3PIK3CDHSD17B10 | |
| SCHEMBL32664209 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL29132972 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL29132969 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL21576380 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL17343011 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL20054305 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL13415865 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL21408129 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CHRM3HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |