Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132972 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2TSHR | |
| SCHEMBL32664209 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2TSHR | |
| SCHEMBL21576380 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2TSHR | |
| SCHEMBL24070656 | 0.83 | CHRM2 (0.42) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL28923136 | 0.83 | CHRM2 (0.42) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL25698997 | 0.83 | CHRM2 (0.42) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL30867239 | 0.81 | CHRM2 (0.38) | CHRM2CHRM1CHRM3NR1H2USP2 | |
| SCHEMBL21227876 | 0.81 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2TSHR | |
| SCHEMBL27319966 | 0.81 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2TSHR | |
| SCHEMBL21227880 | 0.80 | CHRM2 (0.37) | CHRM2CHRM1CHRM3NR1H2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-112118845-B | MCL-1 inhibitors | 吉利德科学公司 | 2023-06-13 | — | — | CN | disclosed |