Quercetin

Quercetin

SCHEMBL2407213

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12.O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.81
KMT2A Q03164 10/20 0.81
KDM4E B2RXH2 8/20 0.81
CYP3A4 P08684 8/20 0.81
HSD17B10 Q99714 8/20 0.81
CYP1A2 P05177 8/20 0.81
ALOX15 P16050 7/20 0.81
MAPT P10636 7/20 0.81
IPMK Q8NFU5 7/20 0.81
IP6K2 Q9UHH9 7/20 0.81
CYP1A1 P04798 7/20 0.81
CYP1B1 Q16678 7/20 0.81
POLH Q9Y253 7/20 0.81
RECQL P46063 6/20 0.81
CYP2C9 P11712 6/20 0.81
HIF1A Q16665 6/20 0.81
APP P05067 6/20 0.81
AKR1B1 P15121 6/20 0.81
TDP1 Q9NUW8 6/20 0.81
ALDH1A1 P00352 6/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL8116614 0.95 MEN1 (0.77) MEN1KMT2AKDM4ECYP3A4HSD17B10
Kaempferol SCHEMBL5251789 0.95 MEN1 (0.75) MEN1KMT2AKDM4ECYP3A4HSD17B10
Luteolin SCHEMBL8161993 0.93 MEN1 (0.72) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL4303275 0.92 MEN1 (0.74) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL27640936 0.91 MEN1 (0.97) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL1545849 0.90 MEN1 (0.72) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL29723041 0.90 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL118425 0.90 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL17629824 0.90 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4HSD17B10
Quercetin SCHEMBL31507620 0.90 MEN1 (1.00) MEN1KMT2AKDM4ECYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011104667-A1 BASIC AMINOACID SALTS OF POLYPHENOLS ANTHEM BIOSCIENCES PRIVATE LIMITED (IN) 2011-09-01 WO disclosed
EP-1534698-B1 FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS ROWETT RES INST (GB) 2007-09-19 EP disclosed
EP-1534698-A1 FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS The Rowett Research Institute (GB) 2005-06-01 EP disclosed
WO-2004082646-A1 METHOD FOR PREVENTING OR REDUCING COLOUR LOSS OF HAIR QUEST INTERNATIONAL SERVICES B.V. (NL) 2004-09-30 WO disclosed
WO-2004007475-A1 FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS ROWETT RESEARCH INSTITUTE (GB) 2004-01-22 WO disclosed
WO-2002094303-A1 POMEGRANATE PRODUCTS USEFUL IN IMPROVING HEALTH AND METHODS OF USE THEREOF RIMONEST LTD. (IL) 2002-11-28 WO disclosed
US-20020012710-A1 Pomegranate products useful in improving health and methods of use thereof RIMONEST LTD. 2002-01-31 US disclosed