Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076019 | 1.00 | AR (0.53) | ARTAS1R3TAS1R1TAS1R2CHRNA4 | |
| SCHEMBL24072704 | 0.88 | AR (0.52) | ARTAS1R3TAS1R1TAS1R2CNR1 | |
| SCHEMBL24072304 | 0.88 | AR (0.52) | ARTAS1R3TAS1R1TAS1R2CNR1 | |
| SCHEMBL24071902 | 0.84 | AR (0.41) | ARHIF1AACACBMAPK14CNR1 | |
| SCHEMBL24075449 | 0.84 | AR (0.41) | ARHIF1AACACBMAPK14CNR1 | |
| SCHEMBL24072743 | 0.83 | AR (0.40) | ARSTAT3HIF1AACACBMAPK14 | |
| SCHEMBL24076113 | 0.83 | AR (0.40) | ARHIF1ANSD2 | |
| SCHEMBL24071934 | 0.82 | HDAC4 (0.43) | AR | |
| SCHEMBL24076486 | 0.82 | HDAC4 (0.43) | AR | |
| SCHEMBL24076011 | 0.75 | MCL1 (0.42) | ARSTAT3HIF1AMAPK14CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239745-A1 | IL-17A MODULATORS | SANOFI (FR) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021239743-A1 | IL-17A MODULATORS | SANOFI (FR) | 2021-12-02 | — | — | WO | disclosed |