Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071902 | 1.00 | AR (0.41) | ARNPC1HIF1AHDAC4HDAC6 | |
| SCHEMBL24071905 | 0.88 | NPC1 (0.48) | NPC1HDAC6CNR1 | |
| SCHEMBL24071896 | 0.88 | NPC1 (0.48) | NPC1HDAC6CNR1 | |
| SCHEMBL24076019 | 0.84 | AR (0.53) | ARNPC1HIF1AMAPK14CNR1 | |
| SCHEMBL24072292 | 0.84 | AR (0.53) | ARNPC1HIF1AMAPK14CNR1 | |
| SCHEMBL24075450 | 0.84 | P2RX7 (0.42) | AR | |
| SCHEMBL24076113 | 0.81 | AR (0.40) | ARHIF1ANSD2CNR2KDM4E | |
| SCHEMBL24072743 | 0.81 | AR (0.40) | ARHIF1AHDAC4HDAC6MAPK14 | |
| SCHEMBL24071934 | 0.80 | HDAC4 (0.43) | ARHDAC4HDAC6CNR2 | |
| SCHEMBL24076486 | 0.80 | HDAC4 (0.43) | ARHDAC4HDAC6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239743-A1 | IL-17A MODULATORS | SANOFI (FR) | 2021-12-02 | — | — | WO | disclosed |