Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074605 | 0.87 | CYP1A2 (0.57) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30339193 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30339330 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30339083 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24072514 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24073804 | 0.85 | NPC1 (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24072542 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24074488 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30339219 | 0.85 | NPC1 (0.62) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL24074132 | 0.85 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |