Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NSD2 | O96028 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074561 | 0.72 | ALDH1A1 (0.76) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL24074836 | 0.68 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL19846480 | 0.64 | KDM4E (0.61) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL23351420 | 0.64 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL24074587 | 0.63 | KDM4E (0.75) | ALDH1A1KDM4EGAAHPGDMAPT | |
| P-Xylene SCHEMBL27879229 | 0.62 | CYP1A2 (0.55) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL22856763 | 0.62 | GAA (0.53) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL11954809 | 0.62 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL28945228 | 0.62 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL9161190 | 0.62 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239191-A1 | PERIMIDINE DERIVATIVES AND USE THEREOF | TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) | 2021-12-02 | — | — | WO | disclosed |