SCHEMBL24074136

SCHEMBL24074136

CC(=O)Oc1ccc(N=O)cc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.65
KDM4E B2RXH2 8/20 0.54
HSD17B10 Q99714 5/20 0.54
ALDH1A1 P00352 5/20 0.54
HPGD P15428 5/20 0.54
TSHR P16473 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
PTGS1 P23219 2/20 0.54
PTGS2 P35354 2/20 0.54
ESR1 P03372 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
HMGB1 P09429 1/20 0.54
GGT1 P19440 1/20 0.54
BLM P54132 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17010343 0.83 CFD (0.59) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL16715329 0.79 CFD (1.00) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL25027 0.79 CFD (0.73) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL344505 0.77 KDM4E (0.74) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL1317371 0.77 CFD (0.71) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL344489 0.77 CFD (0.71) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL1319089 0.76 CFD (0.69) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL1162085 0.76 CFD (0.69) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL329298 0.76 CFD (0.69) CFDKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL31618292 0.76 CFD (0.69) CFDKDM4EHSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021239117-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2021-12-02 WO disclosed