Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338926 | 0.80 | PLK1 (0.49) | ALDH1A1F2RALOX5PTGS2CYP1A2 | |
| SCHEMBL24074261 | 0.80 | PLK1 (0.49) | ALDH1A1F2RALOX5PTGS2CYP1A2 | |
| SCHEMBL24074263 | 0.78 | SCN5A (0.47) | ALDH1A1F2RALOX5PTGS2CYP1A2 | |
| SCHEMBL30339290 | 0.78 | SCN5A (0.47) | ALDH1A1F2RALOX5PTGS2CYP1A2 | |
| SCHEMBL27417295 | 0.77 | ALDH1A1 (0.47) | ALDH1A1ABL1F2RCRBNHTT | |
| SCHEMBL10394666 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ABL1HTTARCYP1A2 | |
| SCHEMBL26325050 | 0.74 | ALDH1A1 (0.50) | ALDH1A1ABL1CRBNHTTAR | |
| SCHEMBL11798071 | 0.74 | ALDH1A1 (0.54) | ALDH1A1ABL1HTTARCYP1A2 | |
| SCHEMBL11343092 | 0.72 | ABL1 (0.55) | ALDH1A1ABL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11604188 | 0.72 | ALDH1A1 (0.53) | ALDH1A1ABL1ALOX5PTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |