Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.57 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20982583 | 0.83 | RHEB (0.70) | RHEBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24075325 | 0.82 | KDM4E (0.73) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL20535350 | 0.82 | RHEB (1.00) | RHEBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3332734 | 0.82 | RHEB (0.69) | RHEBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL20982510 | 0.81 | PKN1 (0.82) | RHEBKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL1842081 | 0.81 | RHEB (0.59) | RHEBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24075316 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL24075246 | 0.80 | ALDH1A1 (0.69) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL198014 | 0.80 | ALDH1A1 (0.69) | RHEBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL38658270 | 0.80 | ALDH1A1 (0.69) | KDM4EALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2021242790-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | EPHX1, EPHX2, NCEH1 | RHEB 1868/4885KDM4E 1761/4885ALDH1A1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.