SCHEMBL24075138

SCHEMBL24075138

C=CCCN(CCC)C(C)=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
TSHR P16473 5/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.35
TP53 P04637 1/20 0.34
CA1 P00915 2/20 0.33
USP2 O75604 1/20 0.32
FAAH O00519 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21896278 0.88 TSHR (0.43) CA12CA2CA9TSHRMAPK1
SCHEMBL27212558 0.85 TSHR (0.35) CA12CA9TSHRALDH1A1CA1
SCHEMBL20997121 0.83 USP2 (0.38) TSHRALDH1A1HPGDUSP2ZDHHC20
SCHEMBL483128 0.82 CA12 (0.55) CA12CA2CA9TSHRMAPK1
SCHEMBL13055369 0.79 CA12 (0.52) CA12CA2CA9TSHRMAPK1
SCHEMBL13055372 0.79 CA12 (0.52) CA12CA2CA9TSHRMAPK1
Hydrochloric Acid SCHEMBL3020939 0.79 CA12 (0.52) CA12CA2CA9TSHRMAPK1
SCHEMBL13055370 0.79 CA12 (0.52) CA12CA2CA9TSHRMAPK1
SCHEMBL23005776 0.79 TSHR (0.39) CA12CA2CA9TSHRALDH1A1
SCHEMBL20459785 0.78 ZDHHC20 (0.44) CA12CA2CA9TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230190-A1 PYRIMIDINE BASED MODULATORS AND USES THEREOF QUANTA THERAPEUTICS, INC. (US) 2023-11-30 WO disclosed
WO-2021241484-A1 WRITING IMPLEMENT 三菱鉛筆株式会社 2021-12-02 WO disclosed