Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.68 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074574 | 0.87 | ATR (0.68) | ATRCHEK1 | |
| SCHEMBL25877326 | 0.86 | ATR (0.67) | ATRCHEK1 | |
| SCHEMBL24075206 | 0.85 | ATR (0.58) | ATRCHEK1 | |
| SCHEMBL24074582 | 0.84 | ATR (0.59) | ATRCHEK1 | |
| SCHEMBL24074565 | 0.84 | ATR (0.68) | ATRCHEK1 | |
| SCHEMBL24075200 | 0.84 | ATR (0.58) | ATRCHEK1ATRIP | |
| SCHEMBL24075497 | 0.83 | ATR (0.59) | ATRCHEK1 | |
| SCHEMBL24075214 | 0.83 | ATR (0.67) | ATRCHEK1 | |
| SCHEMBL24075218 | 0.83 | ATR (0.69) | ATRCHEK1 | |
| SCHEMBL24074558 | 0.83 | ATR (0.57) | ATRCHEK1ATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212165-A1 | FLUOROPYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF | WUXI LIFE FOUNTAIN BIOTECH CO., LTD (CN) | 2023-07-06 | — | — | US | disclosed |
| US-20230212165-A1 | FLUOROPYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF | WUXI LIFE FOUNTAIN BIOTECH CO., LTD (CN) | 2023-07-06 | — | — | US | disclosed |
| WO-2021238999-A1 | FLUOROPYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF | 深圳市瓴方生物医药科技有限公司 | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212165-A1 | FLUOROPYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF | QDPR, DPYD, KCNJ2 | ATR 4257/4885CHEK1 3572/4885ATRIP 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.