Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632430 | 0.78 | PRKDC (0.52) | KDM4EALDH1A1CYP1A2TDP1LMNA | |
| SCHEMBL28821471 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL24075369 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL31028292 | 0.73 | AAK1 (0.42) | KDM4EALDH1A1CYP1A2CYP2D6LMNA | |
| SCHEMBL19640196 | 0.72 | LMNA (0.50) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL24075609 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1USP2CYP1A2CYP2D6 | |
| SCHEMBL23658839 | 0.70 | ERN1 (0.54) | ALDH1A1TDP1LMNAHTTKMT2A | |
| SCHEMBL24269759 | 0.69 | ERN1 (0.46) | KDM4EALDH1A1CYP1A2CYP2D6TDP1 | |
| SCHEMBL13215217 | 0.69 | GAA (0.44) | KDM4ECYP1A2CYP2D6TDP1LMNA | |
| SCHEMBL19640183 | 0.68 | PRKDC (0.70) | KDM4EALDH1A1USP2CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239077-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-12-02 | — | — | WO | disclosed |