Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075522 | 0.91 | HDAC1 (0.39) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24074732 | 0.88 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24075547 | 0.88 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24075653 | 0.88 | HDAC1 (0.38) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24075550 | 0.88 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24075523 | 0.87 | DOT1L (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL28948817 | 0.86 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL28948818 | 0.86 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL24075654 | 0.86 | SLC29A1 (0.34) | SLC29A1HTTPDE4APDE4BPDE4C | |
| SCHEMBL31028256 | 0.85 | SLC29A1 (0.35) | SLC29A1HTTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239077-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-12-02 | — | — | WO | disclosed |