Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548377 | 1.00 | MAOB (0.65) | MAOBHPGDALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1821607 | 0.86 | PNLIP (0.54) | MAOBHPGDALDH1A1MAPK1CYP3A4 | |
| SCHEMBL4456195 | 0.83 | CA12 (0.62) | HPGDALDH1A1MAPK1CYP3A4LTA4H | |
| SCHEMBL9458638 | 0.83 | SRD5A2 (0.54) | MAOBHPGDMAPK1PGRCYP2C19 | |
| SCHEMBL22447136 | 0.83 | POLB (0.64) | MAOBHPGDALDH1A1MAPK1LMNA | |
| SCHEMBL10486770 | 0.83 | POLB (0.47) | MAOBHPGDMAPK1PGR | |
| SCHEMBL6061853 | 0.82 | MCL1 (0.60) | MAOBHPGDALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6062607 | 0.82 | HSP90AB1 (0.60) | MAOBHPGDALDH1A1MAPK1CYP3A4 | |
| SCHEMBL337469 | 0.81 | HPGD (0.71) | HPGDALDH1A1MAPK1CYP3A4LTA4H | |
| SCHEMBL11349079 | 0.81 | HPGD (0.69) | HPGDALDH1A1MAPK1CYP3A4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021238588-A1 | OXATHIAZINE COMPOUND AND USE THEREOF | 四川大学华西医院 | 2021-12-02 | — | — | WO | disclosed |