Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180976 | 1.00 | CHRNB4 (0.43) | CHRNB4CHRNA3P2RX7CYP19A1TOP2A | |
| SCHEMBL24075134 | 1.00 | CHRNB4 (0.43) | CHRNB4CHRNA3P2RX7CYP19A1TOP2A | |
| SCHEMBL10297759 | 0.85 | CHRNB4 (0.40) | CHRNB4CHRNA3P2RX7CYP19A1TOP2A | |
| SCHEMBL13563111 | 0.81 | CHRNB4 (0.38) | CHRNB4CHRNA3P2RX7CYP11B1CYP11B2 | |
| SCHEMBL14661195 | 0.77 | CHRNB4 (0.40) | CHRNB4CHRNA3P2RX7CYP19A1CYP11B1 | |
| SCHEMBL10297556 | 0.77 | CHRNB4 (0.43) | CHRNB4CHRNA3P2RX7CYP19A1CHRNB2 | |
| SCHEMBL24090523 | 0.77 | CHRNB4 (0.43) | CHRNB4CHRNA3P2RX7CYP19A1CHRNB2 | |
| SCHEMBL21000491 | 0.74 | CHRNB4 (0.39) | CHRNB4CHRNA3P2RX7 | |
| SCHEMBL12803718 | 0.73 | P2RX7 (0.39) | CHRNB4CHRNA3P2RX7CYP19A1 | |
| SCHEMBL20646064 | 0.73 | CHRNB4 (0.38) | CHRNB4CHRNA3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |