Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15507033 | 0.82 | ABCB1 (0.38) | ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23878623 | 0.81 | PCSK9 (0.32) | PCSK9CTSL | |
| SCHEMBL32679879 | 0.79 | NPC1 (0.33) | NPC1RAB9ARECQLSMN1; SMN2CTSL | |
| SCHEMBL15507057 | 0.75 | ALDH1A1 (0.35) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL30992460 | 0.71 | ABCB1 (0.41) | MAPTAAK1 | |
| SCHEMBL22858026 | 0.68 | ABCB1 (0.38) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30992642 | 0.65 | ABCB1 (0.38) | ALDH1A1 | |
| SCHEMBL6025129 | 0.64 | NPC1 (0.35) | NPC1RAB9ARECQLSMN1; SMN2AAK1 | |
| SCHEMBL4900478 | 0.62 | AAK1 (0.47) | ALDH1A1MAPTAAK1 | |
| SCHEMBL22828753 | 0.61 | NPC1 (0.39) | ALDH1A1NPC1RAB9ARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |