⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932292 | 0.84 | HTT (0.48) | — | |
| SCHEMBL20548379 | 0.83 | HSD17B10 (0.35) | — | |
| SCHEMBL19514619 | 0.80 | — | — | |
| SCHEMBL20915047 | 0.80 | — | — | |
| SCHEMBL16607686 | 0.80 | HSD17B10 (0.33) | — | |
| SCHEMBL28289520 | 0.80 | HSD17B10 (0.36) | — | |
| SCHEMBL18932289 | 0.77 | HTT (0.41) | — | |
| SCHEMBL20121059 | 0.77 | HTT (0.45) | — | |
| SCHEMBL28125200 | 0.76 | HSD17B10 (0.31) | — | |
| SCHEMBL3891518 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637621-B2 | Long-wearable soft contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2014-01-28 | — | — | US | disclosed |
| EP-1243960-B2 | SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD | COOPERVISION INT HOLDING CO LP (BB) | 2013-10-16 | — | — | EP | disclosed |
| US-20110211158-A1 | Long-Wearable Soft Contact Lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2011-09-01 | — | — | US | disclosed |
| EP-1243960-B1 | SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD | ASAHIKASEI AIME CO LTD (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-6867245-B2 | Long wearable soft contact lens | ASAHIKASEI AIME CO., LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040192872-A1 | Long-wearable soft contact lens | ASAHIKASEI AIME CO., LTD (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1243960-A1 | SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD | ASAHIKASEI AIME CO., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-20020016383-A1 | Long wearable soft contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2002-02-07 | — | — | US | disclosed |