SCHEMBL20121059

SCHEMBL20121059

CCCCCCOCCCCCCO[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.45
THRB P10828 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPT P10636 1/20 0.45
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CES2 O00748 2/20 0.38
USP2 O75604 1/20 0.36
TSHR P16473 2/20 0.35
CES1 P23141 1/20 0.35
SPHK1 Q9NYA1 2/20 0.34
SPHK2 Q9NRA0 1/20 0.34
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18932289 0.96 HTT (0.41) HTTTHRBMEN1KMT2AMAPT
SCHEMBL18932292 0.94 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL29164952 0.81 HTT (0.56) HTTTHRBMEN1KMT2AMAPT
SCHEMBL29164977 0.81 HTT (0.56) HTTTHRBMEN1KMT2AMAPT
SCHEMBL4455209 0.81 ADRB2 (0.42) ALDH1A1TSHR
SCHEMBL9119727 0.78 THRB (0.47) HTTTHRBMEN1KMT2AMAPT
SCHEMBL7172026 0.78 THRB (0.47) HTTTHRBMEN1KMT2AMAPT
SCHEMBL11572901 0.78 THRB (0.47) HTTTHRBMEN1KMT2AMAPT
SCHEMBL77168 0.78 THRB (0.47) HTTTHRBMEN1KMT2AMAPT
SCHEMBL766409 0.78 THRB (0.47) HTTTHRBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963471-B2 Liquid crystal vertical alignment agent, liquid crystal display element and manufacture method of liquid crystal display element SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2018-05-08 US disclosed