Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168567 | 0.89 | NLRP3 (0.64) | NLRP3GPR139AKR1B1 | |
| SCHEMBL24076327 | 0.89 | NLRP3 (0.64) | NLRP3GPR139AKR1B1 | |
| SCHEMBL29426566 | 0.87 | NLRP3 (0.63) | NLRP3GPR139AKR1B1MAPT | |
| SCHEMBL26732911 | 0.87 | NLRP3 (0.63) | NLRP3GPR139AKR1B1MAPT | |
| SCHEMBL24076302 | 0.86 | NLRP3 (0.62) | NLRP3GPR139AKR1B1MAPT | |
| SCHEMBL25748603 | 0.85 | NLRP3 (0.61) | NLRP3RAB9AGPR139AKR1B1 | |
| SCHEMBL25748626 | 0.85 | NLRP3 (0.61) | NLRP3RAB9AGPR139AKR1B1 | |
| SCHEMBL24076421 | 0.84 | NLRP3 (0.60) | NLRP3GPR139AKR1B1MAPTTP53 | |
| SCHEMBL24076330 | 0.84 | NLRP3 (0.60) | NLRP3GPR139AKR1B1MAPTTP53 | |
| SCHEMBL24076373 | 0.84 | NLRP3 (0.60) | NLRP3GPR139AKR1B1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |