Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.37 |
| ▸ | CCRL2 | O00421 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076963 | 1.00 | NLRP3 (0.55) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24077186 | 1.00 | NLRP3 (0.55) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24076330 | 0.91 | NLRP3 (0.60) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24076421 | 0.91 | NLRP3 (0.60) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24076373 | 0.91 | NLRP3 (0.60) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24077190 | 0.90 | NLRP3 (0.54) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24077018 | 0.90 | NLRP3 (0.54) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24076413 | 0.90 | NLRP3 (0.54) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24076956 | 0.90 | NLRP3 (0.54) | NLRP3GPR139AKR1B1CCR2CCRL2 | |
| SCHEMBL24077020 | 0.90 | NLRP3 (0.54) | NLRP3GPR139AKR1B1CCR2CCRL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |