Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24077242 | 0.89 | GRIN2B (0.60) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL30381307 | 0.88 | ALDH1A1 (0.55) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL30381244 | 0.88 | GRIN1 (0.53) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL24077247 | 0.88 | ALDH1A1 (0.55) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL24077271 | 0.88 | GRIN1 (0.66) | GRIN1GRIN2BCCR3 | |
| SCHEMBL24077243 | 0.88 | GRIN1 (0.53) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL24075931 | 0.88 | MEN1 (0.54) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL30381079 | 0.86 | GAA (0.55) | GRIN1GRIN2BCHEK1 | |
| SCHEMBL24076655 | 0.86 | GRIN1 (0.50) | GRIN1GRIN2BCCR3CHEK1THRB | |
| SCHEMBL24077246 | 0.86 | CHEK1 (0.52) | GRIN1GRIN2BCCR3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057053-B | 5-Membered heteroaryl derivatives containing at least one N and pharmaceutical compositions containing the same as active ingredient for preventing or treating mental disorders | 特立尼奥公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116057053-A | 5-membered heteroaryl derivatives containing at least one N and pharmaceutical compositions containing the same as active ingredient for preventing or treating mental disorders | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | disclosed |
| WO-2021241982-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2021-12-02 | — | — | WO | disclosed |