SCHEMBL24078366

SCHEMBL24078366

c1ccc(-c2nc(-c3ccc4c(c3)oc3c(-c5ccccc5)cccc34)nc(-n3c4ccccc4c4cc5c(cc43)C3(c4ccccc4-c4ccccc43)c3ccccc3-5)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965122 0.96 PRKDC (0.33) PRKDCALOX5
SCHEMBL25965146 0.96 PRKDC (0.32) PRKDCALOX5
SCHEMBL25121565 0.95 ALOX5 (0.38) PRKDCALOX5
SCHEMBL25965225 0.94 PRKDC (0.35) PRKDCALOX5
SCHEMBL25965128 0.93 PRKDC (0.33) PRKDCALOX5
SCHEMBL25121899 0.92 ALOX5 (0.34) PRKDCALOX5
SCHEMBL24078118 0.92
SCHEMBL25121760 0.92 KDM4E (0.31)
SCHEMBL25965083 0.92
SCHEMBL24078354 0.91 PRKDC (0.34) PRKDCALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
WO-2021239772-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2021-12-02 WO disclosed