Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413537 | 1.00 | SLC22A6 (0.62) | SLC22A6MAPTGABRR1LMNATSHR | |
| SCHEMBL2414863 | 1.00 | SLC22A6 (0.62) | SLC22A6MAPTGABRR1LMNATSHR | |
| SCHEMBL28243 | 0.90 | TSHR (0.50) | SLC22A6MAPTLMNATSHRHSD17B10 | |
| SCHEMBL15976653 | 0.81 | MGAM (0.50) | SLC22A6MAPTLMNATSHRHSD17B10 | |
| SCHEMBL13908456 | 0.81 | MGAM (0.50) | SLC22A6MAPTLMNATSHRHSD17B10 | |
| SCHEMBL12787282 | 0.81 | MGAM (0.50) | SLC22A6MAPTLMNATSHRHSD17B10 | |
| SCHEMBL5749928 | 0.80 | TSHR (0.48) | SLC22A6MAPTGABRR1LMNATSHR | |
| SCHEMBL4744296 | 0.80 | TSHR (0.48) | SLC22A6TSHRGPR84 | |
| SCHEMBL667017 | 0.80 | TSHR (0.48) | SLC22A6TSHRGPR84 | |
| SCHEMBL9600868 | 0.80 | SLC22A6 (0.68) | SLC22A6MAPTGABRR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106676141-B | Enzymatic preparation method of chiral intermediate (S) -3-hydroxy glutaric acid monoester | 浙江京新药业股份有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-102798656-B | Method for separating 3-hydroxyl glutaric acid monoester enantiomer by high-performance capillary electrophoresis | UNIV SHAOXING | 2014-06-04 | — | — | CN | claimed |
| CN-103361386-A | Method for preparing rosuvastatin intermediate | SUZHOU ENZYMEWORKS INC | 2013-10-23 | — | — | CN | claimed |
| CN-102798656-A | Method for separating 3-hydroxyl glutaric acid monoester enantiomer by high-performance capillary electrophoresis | UNIV SHAOXING | 2012-11-28 | — | — | CN | claimed |
| WO-2011106546-A1 | A PROCESS FOR THE PREPARATION OF ROSUVASTATIN INTERMEDIATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-09-01 | — | — | WO | claimed |
| CN-101805409-A | Polyesterase polymerization process and device | PING DONG | 2010-08-18 | — | — | CN | claimed |
| CN-101143824-B | Process for preparing 3-hydroxyglutarate compound | HENAN YUCHEN FINE CHEMICAL CO LTD | 2010-04-21 | — | — | CN | claimed |
| CN-101143824-A | Process for preparing 3-hydroxyglutarate compound | HENAN YUCHEN FINE CHEMICAL CO (CN) | 2008-03-19 | — | — | CN | claimed |
| CN-114349633-A | Process for the preparation of diesters of glutaconic acid | 华烁科技股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-108358783-B | 3-substituted glutaric diester and preparation method of glutaconic diester | 华烁科技股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-106676141-B | Enzymatic preparation method of chiral intermediate (S) -3-hydroxy glutaric acid monoester | 浙江京新药业股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-108358783-A | 3-substituted glutaric diester and preparation method of glutaconic diester | 华烁科技股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-107011378-A | The preparation method of high-purity statins drug midbody | 南京大学淮安高新技术研究院 | 2017-08-04 | — | — | CN | disclosed |
| CN-106676141-A | Enzymatic preparation method of chiral intermediate (S)-3-hydroxyglutaric acid monoester | 浙江京新药业股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-1163563-C | Cyanoacrylate adhesives containing ester and polymer additives | �����ɷ� | 2004-08-25 | — | — | CN | disclosed |
| CN-1088084-C | Cyanacrylate adhesive | HENKEL KGAA (DE) | 2002-07-24 | — | — | CN | disclosed |
| CN-1280602-A | Cyanoacrylate adhesives containing ester and polymer additives | HENKEL KGAA (DE) | 2001-01-17 | — | — | CN | disclosed |
| CN-1219949-A | Cyanacrylate adhesive | HENKEL KGAA (DE) | 1999-06-16 | — | — | CN | disclosed |
| CN-1194580-A | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 1998-09-30 | — | — | CN | disclosed |
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |