Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407894 | 0.90 | SLC22A6 (0.62) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL15976653 | 0.90 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12787282 | 0.90 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL13908456 | 0.90 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL2413537 | 0.90 | SLC22A6 (0.62) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL2414863 | 0.90 | SLC22A6 (0.62) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL5458599 | 0.88 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL18914896 | 0.88 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL14992884 | 0.88 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1691447 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498915-B | Simple and controllable synthesis method of alpha-carboxyl-omega-hydroxyl polyether | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-106676141-B | Enzymatic preparation method of chiral intermediate (S) -3-hydroxy glutaric acid monoester | 浙江京新药业股份有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-110498915-A | A kind of α-carboxyl-ω-hydroxy polyethers are simple, controllable synthesis method | UNIV SOUTH CHINA TECH | 2019-11-26 | — | — | CN | claimed |
| CN-110407866-A | The manufacturing method of silicon compound | LANXI LISHUN BIOLOGY CO LTD | 2019-11-05 | — | — | CN | claimed |
| CN-105907094-A | Heat-resistant high-elasticity plastic material and preparation method thereof | 金宝丽科技（苏州）有限公司 | 2016-08-31 | — | — | CN | claimed |
| WO-2011106546-A1 | A PROCESS FOR THE PREPARATION OF ROSUVASTATIN INTERMEDIATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-09-01 | — | — | WO | claimed |
| CN-1251114-A | Acid-functionalized polyurethane adducts | DOW CHEMICAL CO (US) | 2000-04-19 | — | — | CN | claimed |
| EP-0961795-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1999-12-08 | — | — | EP | claimed |
| WO-1998037113-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1998-08-27 | — | — | WO | claimed |
| US-12527779-B2 | Prostaglandin E2 (PGE2) EP4 receptor antagonists | DOMAIN THERAPEUTICS (FR) | 2026-01-20 | — | — | US | disclosed |
| EP-4342957-B1 | OIL-RESISTANT AGENT | DAIKIN IND LTD (JP) | 2025-09-03 | — | — | EP | disclosed |
| US-12358951-B2 | Cyclic peptide antibiotics | GENENTECH, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20240141582-A1 | OIL-RESISTANT AGENT | DAIKIN INDUSTRIES, LTD. (JP) | 2024-05-02 | — | — | US | disclosed |
| EP-4342957-A1 | OIL-RESISTANT AGENT | DAIKIN INDUSTRIES, LTD. (JP) | 2024-03-27 | — | — | EP | disclosed |
| WO-1998037113-A1 | ACID FUNCTIONALIZED POLYURETHANE ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1998-08-27 | — | — | WO | disclosed |
| WO-1997046630-A1 | CYANACRYLATE ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-12-11 | — | — | WO | disclosed |
| EP-0168480-A4 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID. | WISCONSIN ALUMNI RES FOUND (US) | 1987-10-08 | — | — | EP | disclosed |
| US-4584270-A | ENZYME CLEAVAGE OF ESTER GROUPING OF 3-HYDROXYGLUTARIC ACID DIESTER, FOLLOWED BY CHEMICAL CONVERSION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0168480-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-01-22 | — | — | EP | disclosed |
| WO-1985003307-A1 | PROCESS FOR PREPARING OPTICALLY-ACTIVE 4-AMINO-3-HYDROXYBUTYRIC ACID | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527779-B2 | Prostaglandin E2 (PGE2) EP4 receptor antagonists | PTGER1, PTGER4, PTGER3 | TSHR 606/4885HSD17B10 1102/4885MGAM 4869/4885 |
| US-12358951-B2 | Cyclic peptide antibiotics | NPPA, LNPEP, CLPP | TSHR 2876/4885HSD17B10 2696/4885MGAM 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.