Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782865 | 0.88 | PRKCI (0.33) | HCAR2PRKCI | |
| SCHEMBL19841043 | 0.79 | PRKCI (0.35) | HCAR2HCAR3PRKCINR1H4PPARG | |
| SCHEMBL19841048 | 0.73 | PRKCI (0.37) | HCAR2HCAR3PRKCIPPARGPPARD | |
| SCHEMBL19841055 | 0.73 | PRKCI (0.35) | HCAR2HCAR3PRKCINR1H4PPARG | |
| SCHEMBL21569598 | 0.72 | PRKCI (0.39) | PRKCIPPARGPPARDPPARATYR | |
| SCHEMBL21569592 | 0.71 | PRKCI (0.35) | HCAR2HCAR3PRKCIGPR35PPARG | |
| SCHEMBL19841041 | 0.70 | GABRP (0.36) | HCAR2HCAR3PRKCINR1H4PPARG | |
| SCHEMBL9228593 | 0.70 | TLR8 (0.38) | HCAR2HCAR3PDE2APDE1APDE1B | |
| SCHEMBL9227489 | 0.70 | TLR8 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19841057 | 0.69 | PRKCI (0.38) | HCAR2HCAR3PRKCIPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192866-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192866-B2 | Synthesis of tetracyclines and analogues thereof | TET1, TET3, MYC | HCAR2 3521/4885HCAR3 3717/4885PRKCI 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.