Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL209153 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15492440 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL212326 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL25118469 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1059882 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL25434872 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL20375020 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13452762 | 0.98 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28961005 | 0.98 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191846-B2 | Methods of treatment utilizing biocompatible nanoparticles and therapeutic agents | CURADIGM SAS (FR) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191846-B2 | Methods of treatment utilizing biocompatible nanoparticles and therapeutic agents | ALB, CD47, CD63 | ALDH1A1 462/4885SMN1; SMN2 523/4885CYP2C9 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.