SCHEMBL2407975

SCHEMBL2407975

[c]1cnc2c(c1)c[c]c1cccnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.41
CCR8 P51685 5/20 0.41
CCR5 P51681 3/20 0.41
LMNA P02545 3/20 0.41
MMP2 P08253 2/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
NFKB1 P19838 1/20 0.41
MMP8 P22894 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407347 0.86 CCR1 (0.45) CCR1CCR8CCR5LMNAMMP2
SCHEMBL25121 0.83 CCR1 (0.54) CCR1CCR8CCR5LMNAMMP2
SCHEMBL67915 0.78 CCR1 (0.64) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2409386 0.76 CCR1 (0.32) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2966046 0.74 CCR1 (0.42) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2519049 0.71 CCR1 (0.43) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2407335 0.71 CCR1 (0.35) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2409957 0.71 CCR1 (0.37) CCR1CCR8CCR5LMNAMMP2
SCHEMBL2513044 0.68 ALDH1A1 (0.47) CCR1CCR8CCR5LMNAMMP2
SCHEMBL23919 0.68 CLK1 (0.39) CCR1CCR8CCR5LMNAMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed