Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ADA | P00813 | 1/20 | 0.57 |
| ▸ | PGK1 | P00558 | 1/20 | 0.51 |
| ▸ | PGK2 | P07205 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924548 | 1.00 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL723793 | 1.00 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL30091060 | 1.00 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL21136929 | 1.00 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL24917326 | 0.91 | ADORA3 (0.67) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL18041228 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL25204813 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL29363191 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL18061792 | 0.89 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2BALOX15 | |
| SCHEMBL21136921 | 0.88 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AADORA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |