Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24082211 | 0.95 | TSHR (0.42) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL25224860 | 0.90 | TSHR (0.40) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL6885929 | 0.85 | TSHR (0.48) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL15987047 | 0.83 | CYP1A2 (0.47) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL11592937 | 0.82 | TSHR (0.58) | TSHRL3MBTL1KMT2ACA1CA2 | |
| SCHEMBL24082217 | 0.82 | TSHR (0.45) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL22631505 | 0.81 | TSHR (0.52) | TSHRL3MBTL1CYP1A2KMT2APOLB | |
| SCHEMBL24081981 | 0.79 | ALDH1A1 (0.38) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL11598804 | 0.77 | TSHR (0.56) | TSHRL3MBTL1KMT2ACA1CA2 | |
| SCHEMBL7518295 | 0.77 | GAA (0.39) | TSHRPOLBGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12331038-B2 | Hexone glucokinase inhibitor and use thereof | SHANDONG XUANZHU PHARMA CO., LTD. (CN) | 2025-06-17 | — | — | US | disclosed |
| EP-3919484-B1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | SHANDONG XUANZHU PHARMA CO LTD (CN) | 2023-05-24 | — | — | EP | disclosed |
| US-20220106299-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | SHANDONG XUANZHU PHARMA CO., LTD. (CN) | 2022-04-07 | — | — | US | disclosed |
| EP-3919484-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| EP-3919484-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331038-B2 | Hexone glucokinase inhibitor and use thereof | GCK, KHK, HK1 | TSHR 4107/4885L3MBTL1 4124/4885CYP1A2 1259/4885 |
| US-20220106299-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | GCK, KHK, HK1 | TSHR 4107/4885L3MBTL1 4124/4885CYP1A2 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.