SCHEMBL2408245

SCHEMBL2408245

[c]1cccc2c1-c1[c]cccc1C2(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9957682 0.88 MEN1 (0.44) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL2408385 0.81 LMNA (0.34) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL2407128 0.81 LMNA (0.33) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL2409924 0.81 LMNA (0.35) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL29070768 0.81 LMNA (0.32) LMNAKDM4EMEN1MAPTOPRK1
Hydrochloric Acid SCHEMBL4235155 0.73 LMNA (0.48) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL6293928 0.72 KDM4E (0.39) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL796811 0.72 MEN1 (0.44) LMNAKDM4EMEN1MAPTOPRK1
SCHEMBL2408315 0.71 LMNA (0.39) LMNAKDM4EMEN1MAPTOPRK1
Hydrazine SCHEMBL4174241 0.71 LMNA (0.50) LMNAKDM4EMEN1MAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed