SCHEMBL2408262

SCHEMBL2408262

[c]1cc2cc[c]c3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ERBB2 P04626 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2408908 1.00 CYP1A2 (0.35) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2408688 0.95 CYP1A2 (0.36) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL1047443 0.88 ALDH1A1 (0.44) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL1353143 0.84 ALDH1A1 (0.48) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2410185 0.84 ALDH1A1 (0.42) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2410430 0.82 ALDH1A1 (0.41) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2237193 0.82 ALDH1A1 (0.44) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2409577 0.82 ALDH1A1 (0.44) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2405885 0.80 ALDH1A1 (0.48) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2236436 0.80 ALDH1A1 (0.48) CYP1A2ALDH1A1THRBHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed