SCHEMBL2408326

SCHEMBL2408326

[c]1ccc2c[c]c3cccc4ccc1c2c34

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409845 0.90 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL2413958 0.88 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL24630 0.87 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL23972 0.87 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Methane SCHEMBL28251706 0.85 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL152947 0.85 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL28296580 0.85 CYP1A2 (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL1046484 0.82 ALDH1A1 (0.33) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL578387 0.82 ALDH1A1 (0.33) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL6537252 0.81 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021079915-A1 TRIAZINE COMPOUND HAVING PYRIDYL GROUP AND PYRIDINE COMPOUND 東ソー株式会社 2021-04-29 WO disclosed
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed