Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083869 | 0.92 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24377888 | 0.92 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083883 | 0.85 | MEN1 (0.59) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083789 | 0.83 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083878 | 0.82 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083870 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24377893 | 0.82 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083783 | 0.81 | AR (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24083774 | 0.81 | AR (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24377980 | 0.81 | AR (0.46) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245193-B1 | HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2021-12-08 | — | — | EP | disclosed |