⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576803 | 0.87 | MAPT (0.43) | — | |
| SCHEMBL2413042 | 0.83 | HCAR2 (0.48) | — | |
| SCHEMBL127082 | 0.81 | — | — | |
| SCHEMBL2410094 | 0.81 | — | — | |
| SCHEMBL2409618 | 0.79 | TSHR (0.60) | — | |
| SCHEMBL7755132 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL2409688 | 0.78 | TSHR (0.61) | — | |
| SCHEMBL7755137 | 0.78 | MAPT (0.61) | — | |
| SCHEMBL10772584 | 0.77 | — | — | |
| SCHEMBL129526 | 0.77 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559716-B1 | PYRAZOLONAPHTHYRIDINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-20100093782-A1 | Pyrazolonaphthyridine derivatives | KANAZAWA HASHIME | 2010-04-15 | — | — | US | disclosed |
| US-7608716-B2 | Pyrazolonaphthyridine derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20060040972-A1 | Pyrazolonaphthyridine derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1559716-A1 | PYRAZOLONAPHTHYRIDINE DERIVATIVE | Grelan Pharmaceutical Co., Ltd. (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1288709-A1 | A thermally bleachable dye for a color photothermographic element | EASTMAN KODAK COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6492076-B1 | UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE | EASTMAN KODAK COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-4018611-A | Non-yellowing antimicrobial compositions comprising diiodomethyl sulfones | METALORGANA ETABLISSEMENT (FL) | 1977-04-19 | — | — | US | disclosed |