SCHEMBL129526

SCHEMBL129526

CCCC[CH]C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
HCAR2 Q8TDS4 4/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.43
TSHR P16473 2/20 0.42
HPGD P15428 1/20 0.42
FAAH O00519 2/20 0.42
ALDH1A1 P00352 4/20 0.41
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131145 0.93 FAAH (0.49) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL4365312 0.91 FAAH (0.51) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL11475767 0.91 FAAH (0.51) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL11378992 0.91 FAAH (0.51) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL9011795 0.91 FAAH (0.51) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL22411216 0.91 FAAH (0.51) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL127082 0.86
SCHEMBL128719 0.84 ATM (0.65) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL130828 0.84 ATM (0.54) MAPTHCAR2ATMNPSR1TSHR
SCHEMBL10773388 0.83 CYP1A2 (0.50) MAPTHCAR2ATMNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6979690-B2 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators PFIZER INC. (US) 2005-12-27 US claimed
US-20030207875-A1 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators PFIZER INC 2003-11-06 US claimed
EP-1325921-A2 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators Pfizer Inc. (US) 2003-07-09 EP claimed
EP-1213282-A1 Substituted imidazolium salts and their use for the inhibition of protein ageing. ALTEON Inc. (US) 2002-06-12 EP claimed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
US-11996445-B2 Carbon nanotube composite, dispersion liquid using same, semiconductor device, method for producing semiconductor device, and wireless communication device and merchandise tag each using semiconductor device TORAY INDUSTRIES, INC. (JP) 2024-05-28 US disclosed
US-20240084106-A1 KNEADED MATERIAL, METHOD OF PRODUCING KNEADED MATERIAL, MOLDED BODY, AND OPTICAL MEMBER FUJIFILM CORPORATION (JP) 2024-03-14 US disclosed
US-20240067846-A1 PHOTOPOLYMERIZABLE COMPOSITION, CURED SUBSTANCE, AND OPTICAL MEMBER FUJIFILM CORPORATION (JP) 2024-02-29 US disclosed
CN-117337322-A Kneaded material, method for producing kneaded material, molded body, and optical member 富士胶片株式会社 2024-01-02 CN disclosed
CN-117279959-A Photopolymerizable composition, cured product, and optical member 富士胶片株式会社 2023-12-22 CN disclosed
US-20230227424-A1 ULTRAVIOLET ABSORBING AGENT, RESIN COMPOSITION, CURED SUBSTANCE, OPTICAL MEMBER, METHOD OF PRODUCING ULTRAVIOLET ABSORBING AGENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
CN-116018373-A Ultraviolet absorber, resin composition, cured product, optical member, method for producing ultraviolet absorber, and compound 富士胶片株式会社 2023-04-25 CN disclosed
US-5342749-A Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1994-08-30 US disclosed
EP-0380144-B1 Process for producing optically active benzene-sulfonamide derivatives YAMANOUCHI PHARMA CO LTD (JP) 1994-01-19 EP disclosed
EP-0487081-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD (JP) 1992-05-27 EP disclosed
EP-0257787-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE BENZENE-SULFONAMIDE DERIVATES YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-04-17 EP disclosed
EP-0380144-A1 Process for producing optically active benzene-sulfonamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1990-08-01 EP disclosed
EP-0257787-A1 Process for producing optically active benzene-sulfonamide derivates YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-03-02 EP disclosed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
US-4241079-A ANTHELMINTICS AND FUNGICIDES ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227424-A1 ULTRAVIOLET ABSORBING AGENT, RESIN COMPOSITION, CURED SUBSTANCE, OPTICAL MEMBER, METHOD OF PRODUCING ULTRAVIOLET ABSORBING AGENT, AND COMPOUND F12, C9, UNC93B1 MAPT 3084/4885HCAR2 523/4885ATM 3646/4885
US-20030207875-A1 Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators HRH4, HRH2, HTR4 MAPT 4851/4885HCAR2 141/4885ATM 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.