SCHEMBL24087757

SCHEMBL24087757

O=C1OC(CSc2ccc(Sc3ccc(SCC4CSC(=O)O4)cc3)cc2)CS1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 6/20 0.33
▸ CTSK P43235 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24087758 0.95 CRBN (0.36) CRBNCTSKLMNAMAPTKMT2A
SCHEMBL22231497 0.87 LMNA (0.41) CRBNLMNAMAPTKMT2A
SCHEMBL22252579 0.75 — —
SCHEMBL24087759 0.72 APEX1 (0.33) LMNAMAPTKMT2A
SCHEMBL83271 0.71 CHRM2 (0.40) CRBNCTSK
SCHEMBL15700020 0.71 CHRM2 (0.40) CRBNCTSK
SCHEMBL22252556 0.71 — —
SCHEMBL1402747 0.67 NR1H2 (0.32) CRBN
SCHEMBL20754783 0.67 — —
SCHEMBL22272189 0.65 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210380553-A1 Method for the preparation of compounds with cyclic monothiocarbonate groups BASF SE (DE) 2021-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380553-A1 Method for the preparation of compounds with cyclic monothiocarbonate groups C1R, C1S, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 CRBN 1141/4885CTSK 3546/4885LMNA 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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