SCHEMBL24088

SCHEMBL24088

[c]1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.65
MAPT P10636 7/20 0.65
GAA P10253 6/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
SNCA P37840 3/20 0.65
ALOX15 P16050 3/20 0.65
BCHE P06276 2/20 0.65
ACHE P22303 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
CYP1A2 P05177 2/20 0.65
POLB P06746 1/20 0.65
CYP3A4 P08684 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
ALOX12 P18054 1/20 0.65
MAOA P21397 1/20 0.65
CNR1 P21554 1/20 0.65
PTGS1 P23219 1/20 0.65
SLC6A2 P23975 1/20 0.65
HTR2C P28335 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237156 0.90 NOX1 (0.50) NOX1MAPTGAAMEN1KMT2A
SCHEMBL25692 0.90 NOX1 (0.68) NOX1MAPTGAAMEN1KMT2A
SCHEMBL1335326 0.90 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL17006488 0.83 NOX1 (0.94) NOX1MAPTGAAMEN1KMT2A
SCHEMBL852792 0.81 NOX1 (0.52) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL1146711 0.81 NOX1 (0.90) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL29352248 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL9114 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2306 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-108493343-B Perovskite film, preparation method thereof and application of film in photoelectric device 清华大学 2020-04-24 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US claimed
EP-2213641-B1 FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2018-05-16 EP claimed
US-5516775-A TO INHIBIT PROTEIN KINASE C CIBA-GEIGY CORPORATION (US) 1996-05-14 US claimed
EP-0233461-B1 4,5,6-Substituted-2-pyrimidinamines AMERICAN CYANAMID CO (US) 1996-03-20 EP claimed
WO-1995026347-A1 THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-05 WO claimed
WO-1995010506-A1 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-04-20 WO claimed
EP-0588762-A1 Use of pyrimidine derivatives as inhibitors of proteinkinase C and antitumor drugs CIBA-GEIGY AG (CH) 1994-03-23 EP claimed
EP-0306411-B1 ETHANONE OXIMES MITSUBISHI KASEI CORPORATION (JP) 1992-12-09 EP claimed
US-4977151-A ANTIULCER AGENTS MITSUBISHI KASEI CORPORATION (JP) 1990-12-11 US claimed
US-4876252-A ADMINISTERING ANTIASTHMATIC OR ANTIALLERGEN AMERICAN CYANAMID COMPANY (US) 1989-10-24 US claimed
EP-0306411-A2 Ethanone oximes MITSUBISHI KASEI CORPORATION (JP) 1989-03-08 EP claimed
EP-0233461-A2 4,5,6-Substituted-2-pyrimidinamines AMERICAN CYANAMID COMPANY (US) 1987-08-26 EP claimed