Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799954 | 0.81 | ALDH1A1 (0.44) | NOTUMNPC1RAB9ANPSR1KDM4E | |
| SCHEMBL24089649 | 0.79 | NQO2 (0.47) | NOTUMPTPN1KIF11NPC1RAB9A | |
| SCHEMBL799940 | 0.79 | ALDH1A1 (0.41) | TNKSPARP1TNKS2PARP2NPC1 | |
| SCHEMBL799605 | 0.77 | ALDH1A1 (0.44) | NPC1RAB9ANPSR1NQO2KDM4E | |
| SCHEMBL10078955 | 0.76 | AHR (0.45) | NOTUMNPC1RAB9ATP53NPSR1 | |
| SCHEMBL799583 | 0.76 | KMT2A (0.44) | NPC1RAB9ANQO2HPGDSMN1; SMN2 | |
| SCHEMBL26781772 | 0.76 | TSHR (0.38) | RAB9ANQO2HPGDERCC5FEN1 | |
| SCHEMBL19699022 | 0.75 | GSK3B (0.46) | HDAC6TNKSPARP1TNKS2PARP2 | |
| SCHEMBL14407359 | 0.75 | TNKS (0.50) | HDAC6TNKSPARP1TNKS2PARP2 | |
| SCHEMBL799604 | 0.74 | NQO2 (0.50) | NPC1RAB9ATP53NQO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |