Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.71 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13277006 | 0.83 | EZH2 (1.00) | EZH2EEDSUZ12 | |
| SCHEMBL13276956 | 0.82 | EZH2 (0.77) | EZH2EEDSUZ12 | |
| SCHEMBL13276967 | 0.81 | EZH2 (1.00) | EZH2EEDSUZ12 | |
| SCHEMBL13277903 | 0.80 | EZH2 (1.00) | EZH2EEDSUZ12 | |
| SCHEMBL22004517 | 0.73 | EZH2 (0.76) | EZH2EEDSUZ12 | |
| SCHEMBL13281991 | 0.73 | EZH2 (1.00) | EZH2 | |
| SCHEMBL13276625 | 0.73 | EZH2 (1.00) | EZH2 | |
| SCHEMBL13276846 | 0.72 | EZH2 (1.00) | EZH2 | |
| SCHEMBL2593249 | 0.72 | EZH2 (0.66) | EZH2EEDSUZ12 | |
| SCHEMBL28542668 | 0.72 | EZH2 (0.76) | EZH2EEDSUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379076-A1 | ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379076-A1 | ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS | AHR, ARNT, CYP1B1 | EZH2 1778/4885EED 1667/4885SUZ12 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.