Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928156 | 1.00 | DNM1 (0.42) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL20869918 | 1.00 | DNM1 (0.42) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL19352945 | 1.00 | DNM1 (0.42) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL22778752 | 0.90 | DNM1 (0.46) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL21214222 | 0.89 | CA12 (0.43) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL22851703 | 0.88 | DNM1 (0.44) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL19558842 | 0.88 | DNM1 (0.50) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL22851010 | 0.86 | DNM1 (0.48) | DNM1EPHX1TSHRMEN1KMT2A | |
| SCHEMBL19352948 | 0.85 | EPHX1 (0.39) | EPHX1TSHRALDH1A1FDPSTHRB | |
| SCHEMBL24045162 | 0.85 | EPHX1 (0.39) | EPHX1TSHRALDH1A1FDPSTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380582-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380582-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | PPM1A, PTP4A1, PPP5C | DNM1 3861/4885EPHX1 2337/4885TSHR 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.