SCHEMBL2409196

SCHEMBL2409196

CC1=CC(C(=O)Oc2cccc3cccc(OC(=O)c4ccc(C)cc4)c23)CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 3/20 0.38
EPHX2 P34913 1/20 0.38
GAA P10253 2/20 0.38
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
MEN1 O00255 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
RAB9A P51151 1/20 0.34
MAPT P10636 2/20 0.34
S100A4 P26447 1/20 0.34
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
CYP1A2 P05177 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2402734 0.92 LMNA (0.41) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2405743 0.89 KMT2A (0.45) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2407059 0.83 KMT2A (0.43) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2407532 0.83 KMT2A (0.44) KMT2AESR1ESR2POLBGAA
SCHEMBL20646378 0.80 ESR1 (0.60) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2404565 0.80 ESR1 (0.43) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2403641 0.80 KMT2A (0.43) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2405755 0.79 ESR1 (0.44) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL12497846 0.79 KMT2A (0.58) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL2406081 0.79 KMT2A (0.47) KMT2AESR1ESR2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US claimed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US claimed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US claimed
WO-2012118510-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS III BASF CORPORATION (US) 2012-09-07 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US claimed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US disclosed
EP-2970521-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2016-01-20 EP disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US disclosed