Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997855 | 1.00 | F11 (0.53) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL16997818 | 0.92 | F11 (0.52) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL16997878 | 0.89 | CMA1 (0.59) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL18476273 | 0.89 | CMA1 (0.59) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL3335950 | 0.86 | F11 (0.55) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL18478507 | 0.86 | CMA1 (0.58) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL16997995 | 0.86 | CMA1 (0.58) | F11CMA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL20901311 | 0.86 | F11 (0.56) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL18476563 | 0.86 | F11 (0.58) | F11TPSAB1TPSD1TPSG1 | |
| SCHEMBL27048030 | 0.86 | F11 (0.58) | F11TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11198673-B2 | Therapeutic compounds and compositions | EXITHERA PHARMACEUTICALS, INC. (US) | 2021-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11198673-B2 | Therapeutic compounds and compositions | KLK5, KLKB1, KLK2 | F11 17/4885CMA1 83/4885TPSAB1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.