Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837013 | 0.82 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL20613908 | 0.82 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL151457 | 0.82 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL18755249 | 0.82 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28190613 | 0.78 | TSHR (0.50) | TSHRCYP2C9ALDH1A1MAPK1TDP1 | |
| SCHEMBL23420244 | 0.77 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL3932401 | 0.75 | TSHR (0.70) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL19142357 | 0.75 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28189976 | 0.74 | TSHR (0.47) | TSHRCYP2C9ALDH1A1MAPK1TDP1 | |
| SCHEMBL3888297 | 0.74 | TSHR (0.62) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126415-B1 | SILICONE ACRYLAMIDE COPOLYMER | JOHNSON & JOHNSON VISION CARE (US) | 2021-12-15 | — | — | EP | disclosed |
| CN-102844401-B | Expandable elastomeric material in the presence of water or oil | 罗地亚管理公司 | 2016-08-31 | — | — | CN | disclosed |