Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764720 | 0.85 | CDC7 (0.43) | MAPTCYP3A4NPSR1HTT | |
| SCHEMBL2414636 | 0.83 | HTT (0.41) | CYP3A4MEN1KMT2ANPSR1HTT | |
| SCHEMBL2408680 | 0.82 | HTT (0.41) | MAPTIDO1MEN1KMT2ANPSR1 | |
| SCHEMBL11677458 | 0.80 | L3MBTL1 (0.48) | MAPTL3MBTL1POLBMAPK1CYP3A4 | |
| SCHEMBL26524314 | 0.79 | SMN1; SMN2 (0.52) | MAPTL3MBTL1POLBMAPK1CYP3A4 | |
| SCHEMBL2407133 | 0.77 | SYK (0.46) | SYKMAPTL3MBTL1POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL2410281 | 0.76 | TDP1 (0.46) | MAPTL3MBTL1POLBMAPK1KMT2A | |
| SCHEMBL13938297 | 0.76 | HTT (0.65) | SYKMAPTL3MBTL1IDO1POLB | |
| SCHEMBL13480435 | 0.76 | MAPT (0.65) | SYKMAPTL3MBTL1IDO1POLB | |
| SCHEMBL15202883 | 0.75 | SYK (0.64) | SYKMAPTL3MBTL1IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106627-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |