Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368488 | 0.85 | HSD17B10 (0.58) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL18576516 | 0.85 | KDM4E (0.62) | HSD17B10KDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL23213705 | 0.84 | HSD17B10 (0.60) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL29845235 | 0.84 | HSD17B10 (0.60) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL24114234 | 0.81 | PTGDR2 (0.43) | HSD17B10LMNAHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL3426834 | 0.81 | PDE5A (0.52) | HSD17B10ALOX15KDM4EHPGDALDH1A1 | |
| SCHEMBL3354341 | 0.78 | HSD17B10 (0.65) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL3905353 | 0.76 | HSD17B10 (0.67) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL14631512 | 0.76 | HSD17B10 (0.67) | HSD17B10ALOX15GLAKDM4EHPGD | |
| SCHEMBL21159736 | 0.76 | NTSR1 (0.45) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340982-B1 | COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS INC (US) | 2021-12-15 | — | — | EP | disclosed |