SCHEMBL240949

SCHEMBL240949

c1ccc(N=NN(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 1/20 0.48
MAPK1 P28482 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 7/20 0.41
KMT2A Q03164 7/20 0.41
RAB9A P51151 5/20 0.41
NPC1 O15118 5/20 0.41
MAPT P10636 4/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
TNNI3 P19429 1/20 0.41
TNNT2 P45379 1/20 0.41
TNNC1 P63316 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL592147 1.00 ALDH1A1 (0.52) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL10582965 0.88 ALDH1A1 (0.47) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL5618506 0.79 ALDH1A1 (0.37) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL1347628 0.78 POLB (0.66) ALDH1A1ALOX15MAPK1TSHRMEN1
SCHEMBL1347624 0.78 POLB (0.66) ALDH1A1ALOX15MAPK1TSHRMEN1
SCHEMBL3027471 0.76 MEN1 (0.70) ALDH1A1MAPK1TDP1MEN1KMT2A
SCHEMBL2446163 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL15151253 0.76 KMT2A (0.64) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL11421300 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15MAPK1TDP1TSHR
SCHEMBL2446165 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15MAPK1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104546773-A High-stability amlodipine benzenesulfonate tablet and preparation method thereof CHINA RESOURCES SAIKE PHARMACEUTICAL CO LTD 2015-04-29 CN claimed
EP-1231510-A2 Printing plate having a radiation-sensitive recording layer on a rolled and embossed aluminium support, and process for the production thereof Agfa-Gevaert (BE) 2002-08-14 EP claimed
EP-0336564-B1 PROCESS FOR SEPARATING METHYL DERIVATIVES OF NAPHTHALENE ACCORDING TO CRYSTALLIZATION UNDER PRESSURE Showa Shell Sekiyu Kabushiki Kaisha (JP) 1993-05-19 EP claimed
EP-0336564-A1 Process for separating methyl derivatives of naphthalene according to crystallization under pressure Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-10-11 EP claimed
US-4671936-A CATION EXCHANGE RESINS, PH INDICATORS; VISIBLE COLOR CHANGE MONITORING; MEDICAL EQUIPMENT AMERICAN STERILIZER COMPANY (US) 1987-06-09 US claimed
US-4650739-A Process for post-treating aluminum oxide layers with aqueous solutions containing phosphoroxo anions in the manufacture of offset printing plates with radiation sensitive layer and printing plates therefor HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-17 US claimed
JP-5072729-A None JP disclosed
CN-110023840-A The method for manufacturing the Lighographic printing plate precursor containing diazonium compound 爱克发有限公司 2019-07-16 CN disclosed
CN-104546773-B A kind of high stability amlodipine besylate tablets and preparation method thereof 华润赛科药业有限责任公司 2018-12-11 CN disclosed
CN-107984936-A A kind of reusable writing material and preparation method thereof 吉林大学 2018-05-04 CN disclosed
CN-105522839-B A kind of reusable water writing paper 吉林大学 2018-02-09 CN disclosed
CN-105500968-B A kind of reusable water writing paper 吉林大学 2017-07-28 CN disclosed
US-9687827-B2 Silicate-coated MFI-type zeolite, method of producing the same, and method of producing p-xylene using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2017-06-27 US disclosed
EP-0105170-A2 Process for the after treatment of aluminium oxide layers with aqueous solutions containing alkali silicate, and its application during the manufacture of supports for offset printing plates HOECHST AKTIENGESELLSCHAFT (DE) 1984-04-11 EP disclosed
US-4387151-A Light-curable mixture and light-sensitive copying material made therewith HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-07 US disclosed
EP-0076984-A1 Developers and process for developing irradiated negative-processing reproduction layers HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-20 EP disclosed
EP-0071881-A1 Process for the production of offset printing plates from light-sensitive material based on diazonium salt-polycondensation products HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP disclosed
EP-0048876-A1 Mixture hardenable by light and photosensible copying material made therewith HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-07 EP disclosed
EP-0018860-A1 Water-developable photopolymerisable film-forming compositions and lithographic plate RHONE-POULENC SYSTEMES (FR) 1980-11-12 EP disclosed
JP-H00572729-A 0001-01-01 JP disclosed